Best Energy Supplements for Chronic Fatigue Syndrome

Best Energy Supplements for Chronic Fatigue Syndrome

Living with chronic fatigue syndrome can be a daunting task. You have to worry about many things, such as your health and well-being. One of the best ways to improve your quality of life is by taking energy supplements for Chronic Fatigue Syndrome.

This blog post will discuss the best energy supplements for chronic fatigue syndrome.

What is the best supplement for Chronic Fatigue Syndrome (CFS)?

1.  Coenzyme Q10

CoQ10 Supplement for Chronic Fatigue SyndromeHow it works

Coenzyme Q10 (CoQ10) is a naturally occurring compound that plays a vital role in energy production and cell health.

It is found in all body tissues but is mainly concentrated in the heart, liver, and kidneys. CoQ10 levels decline with age, and research suggests that low levels may be linked to chronic fatigue syndrome (CFS).

What the research says

While CoQ10 may not be a cure for CFS, it is often recommended as a supplement for people with the condition. Some studies have shown that CoQ10 can help to improve energy levels, reduce fatigue, and protect cells from damage.

Foods to eat

  • meat
  • fish
  • poultry
  • nuts and seeds
  • spinach
  • broccoli
  • legumes

What is Chronic Fatigue Syndrome?

Chronic fatigue syndrome (CFS), also called systemic exertion intolerance disease, is a condition that causes extreme fatigue that doesn’t improve with rest. The exact cause of chronic fatigue syndrome is unknown, but it’s thought to be related to a combination of physical, psychological, and viral factors.

Chronic fatigue syndrome can significantly affect your quality of life and make everyday activities difficult to do.

Chronic Fatigue Symptoms (Systemic Exertion Intolerance Disease)

CFS is also known as myalgic encephalomyelitis (ME), post-viral fatigue syndrome (PVFS), and chronic fatigue and immune dysfunction syndrome (CFIDS).

Chronic fatigue syndrome causes extreme tiredness and prolonged fatigue that doesn’t improve with rest. Physical activity can be especially exhausting and female patients are more prone to Chronic Fatigue Syndrome. Cognitive impairment, post-exertional malaise, and hormonal imbalances are notable symptoms as well.

CFS can also cause various other symptoms, including insomnia, unrefreshing sleep, joint pain, sore throat and headaches. The exact cause of CFS is unknown, but it’s believed to be related to an imbalance in the body’s energy production.

Risk factors include previous bacterial infections or a viral infection. Epstein barr virus in particular has been noted as a risk factor for Chronic Fatigue Syndrome.

There’s no single test to diagnose chronic fatigue syndrome. Instead, diagnostic criteria includes a list of signs and symptoms, and by ruling out other conditions.

Treatment for CFS

While there is no cure for CFS, several chronic fatigue syndrome supplements can help alleviate symptoms.

While chronic fatigue syndrome can be debilitating, the right chronic fatigue syndrome nutritional supplements can make a big difference in managing symptoms.

There are a few supplements that are typically recommended that have evidence from clinical trials. A supplement regimen, focusing on mitochondrial dysfunction, can make a significant difference.

There’s no specific medical treatment for chronic fatigue syndrome, but there are treatments that can help manage symptoms.

These include graded exercise therapy, medication, nutritional intervention, and complementary therapies such as massage and acupuncture.

Be sure to talk to your doctor before trying any chronic fatigue syndrome supplements, as some may not be safe. If you think you may have chronic fatigue syndrome, see your doctor for professional medical advice.

You can manage your symptoms and improve your quality of life with proper treatment.

How do supplements for Chronic Fatigue Syndrome help?

Chronic fatigue syndrome is a complex condition that can be difficult to treat. While there is no one-size-fits-all approach, many people find that supplements can help to ease their symptoms.

Supporting the systems affected by CFS can provide relief as the body heals. Support for energy function in the mitochondria, brain function, muscle soreness, fatigue, and sleep support are a few systems that supplementation can support.

Mitochondrial function, in particular, has been noted as an essential aspect of managing CFS.

It is important to note there is research on these supplements, and we will discuss the study in each section. However, supplements and vitamins are not researched as thoroughly as medications, so the evidence is typically not as strong.

Discuss your CFS with your healthcare provider and see if a supplement might make sense for you to try.

About our ratings:


We look at the research backing each supplement and reference the findings in our suggestions.


A high-quality supplement, herb, and vitamin will typically be a little more expensive because it uses high-quality ingredients. Supplements should be a supplement to your healthy lifestyle and diet and stay as clean and natural as food.

Lower quality vitamins and supplements typically have inferior quality ingredients and fillers that decrease the efficacy.


Supplements can be expensive, but they don’t have to be. We will rate the pricing based on the quality of ingredients and efficacy.

Best Energy Supplements for Chronic Fatigue Syndrome

2.  Magnesium for muscle pain

Magnesium for muscle soreness

How it works

Magnesium is a mineral that plays a vital role in energy production and metabolism. It is also involved in nerve and muscle function. There are different forms of magnesium. The most common are magnesium glycinate, magnesium citrate, and magnesium oxidate. Of the three, magnesium oxidate is the cheapest and least effective form.


Magnesium has been shown to have a possible positive effect on sleep, although the evidence is mixed. Magnesium is also essential in muscle recovery and soreness in athletes.

Magnesium supplements are generally safe, but it is essential to talk to a doctor before taking any supplements, as they can interact with medications.

Foods to eat

Foods rich in magnesium include dark leafy greens, nuts and seeds, fish, and whole grains.

3.  B Complex Vitamin

B-complex for Chronic Fatigue Syndrome

How it works

The B complex vitamins are a group of water-soluble vitamins that play essential roles in energy production, metabolism, and nerve and muscle function. B vitamins are found in food and are also available as supplements. They work together, and taking a complex B vitamin supplement is best.


Some studies show a deficiency in B vitamins in people with Chronic Fatigue Syndrome B12 and B9 vitamins have been shown to positively affect Chronic Fatigue Syndrome in studies.

Foods to eat

Some foods rich in B vitamins include poultry, fish, eggs, dairy, and green leafy greens. You can also find B vitamins in fortified cereals and whole grains.

4.  Probiotics

Seed probiotics for chronic fatigue syndrome

How they work

Probiotics are live microorganisms that are similar to the good bacteria that are found in the gut. Probiotics can be taken as supplements or found in fermented foods like yogurt, sauerkraut, and kimchi. Probiotics help to keep the gut healthy by maintaining a balance of good and bad bacteria.


The research on probiotics and chronic fatigue syndrome is mixed. A recent review showed insufficient evidence to support supplementation as a treatment for CFS.

It is important to note that “insufficient evidence” is just that – there needs to be more research to determine effectiveness.

However, it is essential to note that emerging evidence on the importance of a healthy gut microbiome as a factor in managing chronic inflammation, immune function, and brain function may apply here.

Foods to eat

There are two types of food when supporting a healthy gut – prebiotics and probiotics.

Prebiotics are non-digestible fibers that act as food for the “good bacteria” in our gut. They help to keep the probiotics healthy and balanced. Some prebiotic foods include garlic, onions, bananas, oats, and apples.

Probiotics are live microorganisms that are similar to the good bacteria that are found in the gut. Probiotics can be taken as supplements or found in fermented foods like yogurt, sauerkraut, and kimchi. Probiotics help to keep the gut healthy by maintaining a balance of good and bad bacteria.

5.  Omega 3 supplements

Omega 3 Supplements for Chronic Fatigue Syndrome

What do they do

Omega-three supplements are effective in reducing inflammation, which is a common symptom of chronic fatigue syndrome. Omega-three fatty acids are found in fish oil and can be taken as a supplement.


Studies have shown a decrease in the availability of omega-3s in people with CFS. A recent review indicated that omega-3 supplements improved chronic fatigue syndrome symptoms. Omega-3s have anti-inflammatory properties that can help with CFS symptoms.

Foods to eat

Some foods high in omega-three fatty acids include fish, flaxseed, chia seeds, and hemp seeds. You can also find omega-three fatty acids in olive oil, avocados, and nuts.

6.  Brain support

Brain Support for Chronic Fatigue Syndrome

How does it work?

Brain support supplements provide nutrients essential for brain function and can help to improve cognitive function and reduce fatigue.


Brain support is an emerging area of science. Providing the body with the essential nutrients for cognitive function, such as L-Theanine, has improved attention, memory, and other cognitive functions. However, other studies have shown mixed results.

Foods to eat

Some foods high in L-theanine include green tea, black tea, and oolong tea. Some foods high in L-carnitine include red meat, poultry, fish, and dairy products. You can also find these nutrients in supplements.

7.  Melatonin and Zinc

Sleep support for CFS

How does it help?

There is a strong connection between sleep and chronic fatigue syndrome. People with CFS often have difficulty sleeping, and research has shown that poor sleep can worsen CFS symptoms. Sleep support supplements can help to improve sleep quality and reduce fatigue.


A randomized, double-blind, placebo-controlled study found that melatonin and zinc improved sleep in people with Chronic Fatigue syndrome.

Foods to eat

Some foods high in melatonin include cherries, almonds, bananas, and tomatoes. Some foods high in zinc include oysters, beef, pork, chicken, and beans.


Chronic fatigue syndrome is a debilitating condition that can cause extreme fatigue, muscle pain, cognitive difficulties, and other symptoms. Unfortunately, there is no one-size-fits-all approach to treatment, but many people find that supplements can help to ease their symptoms.

Some of the most commonly recommended supplements for chronic fatigue syndrome include omega-3 fatty acids, magnesium, CoQ10, and B vitamins.

Omega-3 fatty acids are thought to help reduce inflammation, while magnesium can help to improve energy levels and relieve muscle pain.

CoQ10 is an essential nutrient for cellular health, and the B vitamins are necessary for immune system function.

While these supplements may not cure chronic fatigue syndrome, they can often help to improve quality of life by alleviating symptoms. It is important to talk to your medical professional for evaluation and treatment.

Frequently Asked Questions

What vitamins can help CFS?

Vitamin B12 is a nutrient that helps keep the body’s nerve and blood cells healthy and helps make DNA, the genetic material in all cells.

In addition, B12 deficiencies are linked to chronic fatigue syndrome (CFS), so supplements may help reduce fatigue and other symptoms.

Another vitamin that may be helpful for people with CFS is vitamin D. This vitamin helps the body absorb calcium, which is needed for strong bones and muscles.

A lack of vitamin D can lead to fatigue, so getting enough of this vitamin is essential.

Additionally, omega-3 fatty acids are essential for good health and have been shown to improve symptoms of CFS. These nutrients are found in fish oil supplements and can also be obtained by eating salmon, tuna, and other fatty fish.

How do you cure chronic fatigue syndrome?

While there is no known cure for chronic fatigue syndrome (CFS), there are several treatments that can help to improve symptoms and quality of life.

One approach is to use chronic fatigue syndrome supplements, which can help to support energy levels and promote better sleep.

Other regular fatigue syndrome treatments include lifestyle changes, such as exercising regularly and eating a healthy diet.

In addition, stress management techniques such as meditation and yoga can also be helpful. While there is no single cure for chronic fatigue syndrome, the condition can be managed effectively with a combination of approaches.

What is the best multivitamin for CFS?

Many experts agree that taking a multivitamin can be beneficial for CFS sufferers. While there are many different brands and formulations on the market, brands with whole food sources and are free of artificial additives are the healthiest option.

In addition, whole food supplements are designed to be easily absorbed by the body. As a result, they are often the most effective form of chronic fatigue syndrome treatment available.


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